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When combined with exercise, NNB's research shows that dihydroberberine supplementation led to powerful antioxidant effects: [2] A remarkable 34.2% decrease in Reactive Oxygen Species (ROS) compared to the exercise-only group Enhanced antioxidant enzyme activities , suggesting improved cellular protection against oxidative damage This reduction in oxidative stress is particularly noteworthy because elevated ROS levels are often associated with metabolic dysfunction and can impair athletic recovery

Pelissero C, Lenczowski M, Chinzi D, Davail-Cuisset B, Sumpter J, Fostier A

Given their broad range of effects and comparatively few side-effects, GLP-1 analogs continue to be the most promising target for diabetes therapy in the past 2 decades

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