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During shortages of Wegovy, Ozempic, Mounjaro, and Zepbound, the FDA exercised temporary enforcement discretion , allowing compounding pharmacies to help meet patient demand. Once manufacturing stabilized: Semaglutide injection products were removed from the FDA Drug Shortage List Tirzepatide injection products were formally declared resolved Compounding reverted to pre-shortage federal and state limits Broad, shortage-based compounding is no longer allowed in 2026

This has led to Victoza and Saxenda lawsuits

Semaglutide has been associated with a small risk of pancreatitis, a potentially serious inflammation of the pancreas

Weight loss results from the ensuant reduction in calorie consumption