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Singh said

Other potential causative mechanisms may also include hormonal dysregulation due to exposure to Bisphenol A (BPA) and other contaminants found in food packaging, which, in turn, contribute to alterations to the gut microbiome, as well as other changes along the gut-brain axis (35)

The samples were stored at 20 for 2 minutes and grinded at 60 HZ for 2 minutes

Other studies have shown issues with the ability of the enzyme dopamine beta hydroxylase which catalyzes dopamine into norepinephrine and the norepinephrine transporter enzyme which is involved in the reuptake of norepinphrine into the synaptic terminals (13, 14)