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Description

This could in turn increase the production of ROS that might be mitigated by the increase that is seen in SOD1 [117]

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It is the key molecule mediating the specific uptake and accumulation of cisplatin in renal and cochlear tissues, as well as the core initiating factor of cisplatin-induced acute kidney injury and ototoxicity (Harrach and Ciarimboli 2015)

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To this end, endorectal US (ERUS) has been utilized both as a diagnostic and therapeutic modality in the management of fistulizing Crohn disease

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