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Semaglutide helps: Reduce appetite , so you feel full sooner Slow down digestion , meaning food stays in your stomach longer Increase insulin release , which lowers blood glucose in people with type 2 diabetes This combination along with lifestyle changes, a healthy diet and exercise makes semaglutide effective for losing weight and controlling blood sugar levels

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GHSR-1a activation in the hypothalamus triggers CRH release, which then hits anterior pituitary corticotrophs, producing ACTH and downstream cortisol elevation

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