Mast cell activation syndrome (MCAS) flares up when mast cells, which are located throughout the body, inappropriately release excessive amounts of chemical mediators, such as histamine, in response to a trigger, including one or more of the following: Alcohol An allergen Certain chemicals Certain food items (which vary among individuals) Certain fragrances (such as perfume or cologne) Certain medications Exposure to sunlight Heat or cold Heavy metals Infection (bacterial, viral, or fungal) Mold/fungus When mast cells function as they should, they help defend the body against threats, such as harmful viruses, bacteria, and fungi
doi: 10.1016/j.jaci.2008.08.020 77
But when researchers dug into the science to see if this peptide BPC-157 lives up to the hype, the answer was a whole lot of not so fast. In research quality, thats the lowest level of evidence we have, the newsletter explained
[5] Notably, that particular study used repeated GHK-Cu injections into wound chambers an important detail we return to below, because it is one of the few places where injected GHK-Cu was actually studied, and it was in rodents, not human skin
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