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While further research is required to delineate the specific conditions under which glutamine supplementation may exert maximal immunomodulatory effects in different cancer types, these immune-enhancing effects hold promise for optimizing the hosts defense mechanisms against cancer cells and potentially enhancing the efficacy of immunotherapeutic interventions

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Accordingly, these carriers regulate the efflux from the brain to plasma of glutamine and acidic AAs, mainly glutamate which can be neurotoxic at high levels

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