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Vitamin B12 - Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline - NCBI Bookshelf

They can assess whether the symptoms are genuinely related to the supplement, investigate alternative causes, and determine the most appropriate management strategy

Jun 2014;28(6):781-9

A reversed-U dose-response, where less works better than more, is the opposite of the more is stronger instinct a vial of research chemical sells on, and it is exactly the kind of inconvenient texture that only shows up when a compound is actually put through controlled trials