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Mazdutide is an oxyntomodulin analogue administered subcutaneously once a week ( In a 24-week phase 2 study investigating the effects of mazdutide on Chinese participants with overweight or obesity, there is a dose response effect, with a mean weight loss of 7.2%, 10.6%, and 11.6% at 3.0 mg, 4.5 mg, and 6.0 mg, respectively, compared to 1.0% with placebo ( 3.5.2 Pemvidutide Pemvidutide is a dual GLP-1 and glucagon receptor co-agonist that is subcutaneously administered once a week