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A Root Cause Medicine Approach: A Comprehensive Guide On How To Test For Low Nitric Oxide Levels

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In some embodiments, a concentration of the otoprotectant is in a range of about 0.1 mM to about 100 mM, about 1 mM to about 100 mM, about 10 mM to about 100 mM, or about 50 mM to about 100 mM

The former induces muscle atrophy by hydrolyzing myosin within myofibrils, while the latter may inhibit protein synthesis by downregulating the expression of eIF3f and MyoD, leading to muscle atrophy (71,72)