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Notably, a recent in vitro study reported that application of porcine-derived collagen peptides increased integrin 21 expression in keratinocytes and dermal fibroblasts and activated an ERKFAK signaling cascade during wound closure, suggesting that collagen peptides may influence integrin-related processes relevant to matrix remodeling and repair [49]

and DsbD Cys 103Cys 109, a CSD which is the active site disulfide in the N-terminal domain of DsbD, which is reduced in vivo by the Trx-like C-terminal domain of DsbD