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Next, we investigated the effects of HnB exposure on testis antioxidant response and our results indicate activation of NRF2-dependent machinery, including catalase (CAT), superoxide dismutase (SOD), glutathione reductase (GSSG-Red), and NADPH quinone reductase (NQO1), whereas no significant changes were observed for glutathione peroxidase (GSH-Px) in testicular tissue

By varying the treatment duration from 10 to 240 seconds, the authors found that a 20-second reduction time offered the highest sensitivity for detecting NH at ppm levels, while longer durations enhanced stability and recovery but decreased sensitivity

10.7759/cureus.29696 45 HuotJ.HouleF.MarceauF.LandryJ