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Resveratrol inhibit the activation of microglia that lead to the release of various pro-inflammatory factors, the production of reactive oxygen species, and the activation of signal pathways leading to neuroinflammation [96] in in vitro resveratrol modulates the inflammatory response at moderate to high concentrations within intestinal cells by down-regulating NF-B activation and preventing mitochondrial dysfunction

Moleiro J, Mo de Ferro S, Ferreira S, Serrano M, Silveira M, Dias Pereira A

To make matters worse, for alcoholics suffering from depression, it also leads to poor response to antidepressant medication

Philadelphia: Lippincott, Williams & Wilkins