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In particular, mitochondrial dysfunction is present in at least one-half of individuals with autism, and is also common in the related conditions

When faced with such a prospect, a 24-h clear liquid diet does not seem to pose an equal risk or inconvenience. The bottom line is this: the most risk-mitigating approach based on the evidence would be to have patients fast for longer (ideally no solids for 24 hours and no liquids for perhaps longer than 2 hours)

(part (c) in Figure 13.4 "Dissolution and Precipitation")

This so-called incretin effect is attributed to the insulinotropic action of gut hormones, particularly: Glucose-dependent insulinotropic polypeptide (GIP) Glucagon-like peptide 1 (GLP-1)