The conventional concern that glucagon raises blood glucose and would offset the glucose-lowering goal of GLP-1/GIP agonism is addressed in the published mechanism literature by examining the tissue-specific and timing-specific actions of each receptor arm
The volume determines your concentration, which determines how much you draw for each dose
J Cell Mol Med 2009 (in press)
Besler C, Heinrich K, Rohrer L, Doerries C, Riwanto M, Shih DM, Chroni A, Yonekawa K, Stein S, Schaefer N, Mueller M, Akhmedov A, Daniil G, Manes C, Templin C, Wyss C, Maier W, Tanner FC, Matter CM, Corti R, Furlong C, Lusis AJ, von Eckardstein A, Fogelman AM, Luscher TF, Landmesser U