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Description

To prevent excess accumulation of cellular debris, that is responsible for cell death

This snowball effect can disrupt a cells integrity, causing it to behave abnormally

Hormonal imbalance : Rarely, excessive growth hormone can elevate IGF-1 beyond safe thresholds

As for mortality, both SGLT-2 inhibitors and GLP-1RA are similar in reducing both total and CV deaths, but SGLT-2 inhibitors only are superior to DPP-4 inhibitors for both deaths, whereas GLP-1RA are superior to DPP-4 inhibitors for total death, but equal for CV death