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It is naturally found in human plasma, saliva and urine, and its level decline as we age

Effect of the Pineal Gland Peptide Preparation Epithalamin on the Lifespan and Spontaneous Tumour Incidence in Female SHR Mice Mechanisms of Ageing and Development Epithalamin treatment begun in old age increased mean lifespan of female SHR mice by 12.3%, reduced spontaneous tumour incidence, and inhibited tumour growth rate extending maximum lifespan

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Ascorbate interacts with small-molecule antioxidants, including tocopherol, glutathione, and thioredoxin