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Notably, treatment with NAC reinstated system xCT activity, normalized glutamate concentrations, and ameliorated behavioral deficits, such as impaired prepulse inhibition and social interactions [77]

Semaglutide (Novo Nordisk A/S, Denmark) is a human glucagon-like peptide-1 (GLP-1) analog in phase III clinical development for the treatment of type 2 diabetes [18]

Combined, these studies involved fewer than 30 human subjects and lacked control groups none used a randomized, placebo-controlled design

Multifocal electroretinogram The mfERGs were recorded using a VERIS 6.0 system (Electro-Diagnostic Imaging, Redwood City, CA, USA) at 5, 8, and 12 W