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In 2004, researchers conducted a meta-analysis of 61 randomized controlled trials evaluating GLP-1 RAs, sodium-glucose co-transporter-2 inhibitors (SGLT2i), dipeptidyl peptidase 4 inhibitors (DPP-4i) and didnt find an increased risk of diabetic retinopathy events with GLP-1 RAs or any of the other classes of antihyperglycemic medications

Al, obese Zucker rats were received a dose of 500 micrograms/kg of body weight over the course of 19 days

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It works by mimicking the functions of two incretin hormones, glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP)