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Wu S, Zhang K, Liang Y, Wei Y, An J, Wang Y et al (2022) Nano-enabled tumor systematic energy exhaustion via zinc (II) interference mediated glycolysis inhibition and specific GLUT1 depletion

This process leads to the activation of macrophages, the secretion of inflammatory factors, and ultimately, inflammation in cells such as Kupffer cells, as well as hepatocytes, which produce significant amounts of cytokine, particularly TNF- and IL-6 (Allam et al