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The treatment normalized neurotransmitter levels (norepinephrine, dopamine, serotonin), highlighting its potential in ameliorating AD-like symptoms ( In vivo , HJG shortened swim times in the Morris Water Maze and increased phosphorylated CREB levels in A-injected Wistar rats, demonstrating its neuroprotective potential (Tian et al., 2021)
Several major platforms have adjusted pricing, changed their medication offerings, or shifted toward brand-name prescriptions as a result
Several other actions of metformin that are independent of glucose metabolism have been reported
Biomedicines 2022,10, 265 29 of 38 Table 4
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