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cells seeded x PE) as previously described ( 2.8 Assessment of cell cycle Cells were seeded into 12-well plates at optimised densities (HCT116: 150,000 cells/well, SW837: 200,000 cells/well) in cRPMI and allowed to adhere overnight at 37C in 5% CO 2 /95% humidified air

FIGURE 1 On the other hand, the paw withdrawal reflex in response to the cold stimulus in the rats receiving flumazenil and naloxone alone was not considerably different from the CCI group (Figure 1C)

KPV stands for lysine-proline-valine

Menopause has also been suggested as a factor that increases the probability of maintaining normoprolactinemia after dopamine agonist therapy is stopped.18 Unless there is evidence of growth of a prolactinoma or related symptoms, such as headache, there is no indication to continue dopamine agonist therapy after menopause.18 There are no significant differences in age, sex, initial dopamine agonist dose or length of treatment between those with continued normoprolactinemia and those with recurrence of hyperprolactinemia.18 We suggest that the dopamine agonist dose be decreased after 2 or 3 years of normal prolactin levels and that therapy be stopped if the prolactin levels remain unchanged after 1 year at the reduced dose