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Discuss any concerns you have about potential side effects with your doctor

In clinical trials, nausea was reported in about 44% of people taking higher doses of semaglutide, while vomiting affected roughly 25%making these two of the most common side effects

[4] [1] The most common injection site reactions include: Erythema (redness) : Localised redness surrounding the injection site, typically appearing within minutes to hours after administration Pruritus (itching) : Mild to moderate itching at or around the injection site Swelling or induration : Raised, firm areas of skin that may persist for several hours Pain or tenderness : Discomfort ranging from mild sensitivity to more pronounced soreness Bruising (ecchymosis) : Small haematomas resulting from minor blood vessel trauma during injection Most injection site reactions develop within 24 hours of administration and resolve within 23 days without specific treatment

The control group received the same amount of aluminum hydroxide diluent