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In reactive astrocytes, MAO-B activity is notably elevated, leading to increased production of H 2 O 2 , while NADPH oxidase 2 is frequently upregulated, further amplifying ROS generation [359, 363]

Histopathological analyses To further evaluate the histological changes in the arthritic joints, the mice were euthanized at the end of the experiment (day 38)

The activity and transcript abundance of glutathione peroxidases, which convert reduced glutathione (GSH) to oxidized glutathione (GSSG), increased in infested resistant plants

Vigorous agitation introduces foam and can destabilize protein and peptide solutions