It could very well be co-existing conditions or habits in B12-deficient folks, which are causing the weight gain
Potential side effects may include injection-site redness, swelling, bruising, itching, tenderness, small lumps, headache, fatigue, nausea, appetite changes, abdominal discomfort, stool changes, dizziness, altered sleep, mood changes, or feeling off. Allergic or immune reactions are also possible, and the FDA has specifically raised concerns about immunogenicity and peptide-related impurities in compounded BPC-157
Because TRT Nation includes B12 in every compounded tirzepatide prescription and starts all patients at conservative doses with a slow titration schedule, most patients find that any nausea is mild and improves significantly within the first few weeks of treatment
Investigating the interaction of BPC 157 with the gut-brain axis could provide valuable insights into its effects on cognitive functions and neuronal health