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Several factors make magnesium particularly relevant for GLP-1 users

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The boxed warning for thyroid C-cell tumors applies to both semaglutide and tirzepatide based on rodent studies whether that translates to human medullary thyroid carcinoma risk has not been established, but the contraindication for personal/family history of MTC or MEN 2 is firm

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Sukhanov S, Higashi Y, Shai SY, Vaughn C, Mohler J, Li Y, Song YH, Titterington J, Delafontaine P

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1993;101(1 Suppl):143S-147S

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