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2022 Apr 26;23(9):4783

Factor 2: Injection speed Reviews mentioning "slow injection over 30-45 seconds" report 28% less soreness than those describing "quick push in 5-10 seconds." The mechanism: slower injection allows tissue expansion and reduces mechanical trauma

47 Taken together, these reports strongly suggest a correlation between sensory nerve ingrowth, inflammatory mediators, and discogenic LBP

In summary, FOXO4-DRI exerts its anti-aging effects by inhibiting the binding of FOXO4 to P53, promoting P53 phosphorylation, and facilitating the translocation of p-P53 from the nucleus to the cytoplasm for its functional role