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(4) combining drug delivery with local CSF removal ("pharmacodialysis") to clear the affected/treated tissue

These findings suggest that the PI3K/AKT/mTOR pathway exerts organ-specific regulatory effects on ferroptosis and the progression of sepsis

These three enzymatic activities are the biotin carboxylase (BC), the carboxyltransferase (CT), and the biotin carboxyl carrier protein (BCCP) activities

Membranes were then probed with horseradish peroxidase-conjugated secondary antibodies antirabbit IgG (Abcam, A16035, 1:5,000) or antimouse IgG (Abcam, A16011, 1:5,000) and developed using enhanced chemiluminescence substrate (Bio-Rad, 170-5060)