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Apart from the potent GH-releasing action, ghrelin has other actions including stimulation of lactotroph and corticotroph function, influence on the pituitary gonadal axis, stimulation of appetite, control of energy balance, influence on sleep and behavior, control of gastric motility and acid secretion, influence on exocrine and endocrine pancreatic function as well as on glucose metabolism, cardiovascular actions and modulation of proliferation of neoplastic cells, as well as of the immune system

doi: 10.1016/j.ajps.2018.05.011 85 De LeoVMilanoFAgostianoACatucciL

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In a 2012 study, 64 adults were given 600 mg per day for 60 days, which significantly reduced cortisol levels compared to placebo