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The ultimate goal is to generate clinical evidence that leads to official changes in treatment guidelines, ensuring that injection frequency is based on patient-reported symptoms and individual clinical response, rather than solely on national blanket protocols

(7) Ogru E, Wilson J C, Heffernan M, Jiang W J, Chalmers D K, Libinaki R, Ng F (2000) The conformational and biological analysis of a cyclic anti-obesity peptide from the C-terminal domain of human growth hormone The Journal of Peptide Research, 2000 Dec, Volume 56 (Issue 6), Pages 388-97

In obese animal models with suppressed beta-3 receptor levels, treatment restored receptor expression to levels comparable to lean controls