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In case of small number of samples that must be analyzed it might not be that important, however, when we look at the number of samples used for meta-analyses involving thousands of individuals the savings of time and laboratory single-use materials seem to be more spectacular

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Namely, KEAP1 is a redox biosensor utilizing reactivity of sulfur atoms, switching on the NRF2-mediated transcriptional activation of cytoprotective genes in response to the redox disturbance