Acknowledgements: This research was supported by a grant from Ministry of Science, Education and Sports, Republic of Croatia and there is no existing personal conflicts of interest with any of the authors
Immune checkpoint inhibitors have shown good therapeutic efficacy in most malignancies, but have limited efficacy in patients with ovarian cancer
In a cellular model of dopamine neurotoxicity induced by fisetinone, silencing of PGC-1 expression was found to significantly increase the protein expression levels of PINK1, parkin, and their phosphorylated proteins (Peng et al., 2019)
Por un lado, esta sustancia vital protege las clulas inmunes del ataque oxidativo y, por otro, aumenta la actividad de, entre otros, las clulas NK o los linfocitos T colaboradores, fortaleciendo as el sistema inmunitario