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Nature (2009) 460:74852.10.1038/nature08185 24 PurcellSMMoranJLFromerMRuderferDSolovieffNRoussosPet alA polygenic burden of rare disruptive mutations in schizophrenia

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Research has focused on energy homeostasis, body composition and metabolic pathway modulation via simultaneous engagement of all three incretin-related receptors

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Weight loss plateaus happen with both orforglipron and tirzepatide

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