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Understanding Acne and its Causes Acne is caused by the interplay of four main factors: excess oil production, clogged hair follicles by oil and dead skin cells, bacteria (specifically, Propionibacterium acnes), and inflammation

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Reconstituted peptides in bacteriostatic water stay stable for roughly 28 to 30 days at 2 to 8C

I'm not one for expiry dates but do use my initiative regarding expiry dates