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Carnitine is a naturally occurring amino acid derivative that plays a crucial role in energy production by transporting fatty acids into mitochondria, where they are converted into energy

It has been shown that the activation of Akt and PI3K in IGF-1/AKT pathway, which can activate mTORC1, results in the inhibition of autophagy, whereas the activation of LKB1, TSC1, or TSC2, which are negative regulators for mTORC1 activity, can all result in the activation of autophagy 45 , 46

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Dietary restriction and 2-deoxyglucose administration reduce focal ischemic brain damage and improve behavioral outcome: evidence for a preconditioning mechanism