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Ocaliva, a farsenoid X receptor agonist, won the FDAs accelerated approval for PBC in May 2016

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Even so, some scientists tell C&EN that amyloid therapies have been important forerunners, pushing the field toward better diagnostics, better tools to monitor brain pathology, and better trial design

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These alterations preserve approximately 97% sequence homology with native human GLP-1 [18]

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