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In 2023, Lopez-Otin proposed twelve markers of aging, including genomic instability, telomere loss, epigenetic changes, loss of protein balance, failure of macroautophagy, dysregulated nutrient sensing, mitochondrial dysfunction, cell senescence, stem cell depletion, altered intercellular communication, chronic inflammation, and dysbiosis

Numerous peptide growth factors are supposed to influence angiogenesis, and thereby wound healing and tissue regeneration

Copper peptides directly address these age-related concerns by activating fibroblasts, the cells responsible for producing collagen and elastin

Late Follicular Phase, Fol2