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To bridge this knowledge gap, future studies would need to focus on developing and validating already established clinically relevant animal models on large animals that better reflect human disease and allow for the study of long-term outcomes and tissue repair to set the stage for future human trials (Gonzalez et al., 2015

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Left unchecked, free radicals damage cells, destabilize the immune system, and contribute to the development of serious health problems

Resveratrol serves as a protein-substrate interaction stabilizer in human SIRT1 activation (in Eng)