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A2 ARs reduced SorLA-dependent regulation of mature APP sorting by interfering with the co-localization and contact between SorLA and mature APP with G protein-associated signaling [137]

phospholipase C (PLCs) participate in cellular signaling and regulation by virtue of their ability to hydrolyze membrane phospholipids into di-acyl-glycerol (DAG) and inositol triphosphate (IP3), which further causes the activation of other signaling pathways involved in various processes, including immune response

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1 Introduction Cell death maintains balance in morphogenesis by clearing damaged or obsolete cells during a state of physical health or illness (Zhu et al., 2024b)