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The redox-sensitive cysteine and its corresponding resolving cysteine are located on the same polypeptide to generate an intermolecular disulfide bond

doi: 10.3389/fnut.2025.1615671 Received 21 April 2025 Accepted 29 July 2025 Published 13 August 2025 Volume 12 - 2025 Edited by Ismael San Mauro Martn, CINUSA Group, Spain Reviewed by Simone Birgit Bayer, University of Otago, Christchurch, New Zealand Emanuela Ribichini, Sapienza University of Rome, Italy Aleksandar Sic, Advocate Illinois Masonic Medical Center, United States Updates Copyright 2025 Khan, Brnstad, Hillestad, Steinsvik, Hausken, Berentsen and Lied

Gentiana Scabra root extracts induce GLP-1 secretion in human cells via a G-protein subunit-mediated route, resulting in the release of GLP-1 and insulin, which mitigate hyperglycemic condition in a type 2 diabetes mice model