In NAFLD/MASLD, antioxidant approaches (vitamin E, glutathione) show modest biochemical and histological benefit mainly in earlier, non-cirrhotic stages, but robust outcome data in advanced disease are lacking ( Our finding that treatment duration did not influence outcomes across multiple analytic approaches (correlation analysis, stratified analysis, multivariate regression, machine learning) has important clinical implications
Samples were stained according to the manufacturers instructions (Maxpar Phospho-Protein Staining PRD016) and acquired on a Helios mass cytometer (Standard Biotools)
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Emerging role of mitochondrial DAMPs, aberrant mitochondrial dynamics and anomalous mitophagy in gut mucosal pathogenesis
