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The GIP-induced peripheral promotion of positive energy balance is likely to be far less effective than the GLP- 1/GIP dual agonist's direct action on the central nervous system, which results in satiety and weight loss
The practical guidance most clinicians give: don't overthink it
It forces patients to jump through hoops and pits them against a massive bureaucracy
Sun exposure (UV) the biggest cause of tan, dark spots and melasma Hormonal change pregnancy, contraception or thyroid issues can trigger melasma Post-inflammatory marks after acne, injury or irritation (common in Indian skin) Ageing & lifestyle cumulative sun damage, pollution and dullness over time Honest framing: Your genetic/ethnic skin tone is natural and healthy it isnt a cause to be fixed
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