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Over the past few years, it has been appreciated that the upper gastrointestinal symptoms that are consistent with gastroparesis may arise from diverse gastric motor dysfunctions that constitute potential targets for pharmacological agents, thus, expanding the spectrum of therapeutic approaches

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Peter Lurie, a former FDA associate commissioner and executive director of the Center for Science in the Public Interest, said there is no real evidence that people need these intermediate doses or that whatever it is they add to the GLP-1 actually makes a meaningful difference. Additionally, documents obtained by the Chronicle show that Empower at one point advised physicians on the specific changes they can list on the prescription