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[DOI] [PubMed] [Google Scholar] 77.Hoxha B., Hoxha M., Domi E., Gervasoni J., Persichilli S., Malaj V., Zappacosta B

What matters most is the overall pattern on your plate

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10 Synthesis and future outlook: rediscovering dormant biology in the era of peptide engineering The cumulative evidence reviewed across metabolic, appetite-regulatory, bonemusclefat, neuroendocrine, and immunemetabolic peptide systems support a unifying conclusion: the apparent scarcity of transformative peptide therapeutics is not a consequence of limited biological opportunity, but rather of historical constraints in pharmacologic execution, translational strategy, and conceptual framing