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Supplementation of LAC can induce neuroprotective and neurotrophic effects of the peripheral nervous system by increasing the level of brain-derived neurotrophic factor (BDNF), especially in the hippocampus and prefrontal cortex (9395)

However, there was no difference in Frailty Index and hand grip test scores between supplemental L-carnitine and placebo groups

Standard clinical escalation protocol The Phase 2 trial published in the New England Journal of Medicine established the titration schedule that most researchers follow

Remember, a well-balanced diet typically provides sufficient nutrients, but in certain cases, supplementation with L-carnitine could be beneficial