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If approved, retatrutide may be used as a treatment for type 2 diabetes and as a weight loss medication

This multi-pathway approach - enhancing central access, synergizing at neuronal targets, and activating complementary energy expenditure pathways - provides a more robust physiological foundation than GLP-1 mono-agonism, justifying the stronger clinical evidence and the higher confidence in its substantial efficacy profile

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GLP-1 (Glucagon-like peptide-1) Receptor: GLP-1 is another incretin hormone known for stimulating insulin release, suppressing glucagon secretion, slowing gastric emptying, and promoting satiety