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It also stimulates the overexpression of the transient receptor potential melastatin 2 (TRPM2) ion channels, triggering macrophage activation, leading to a systemic immune response

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For instance, a case series involving 12 women with interstitial cystitis reported symptom improvement after bladder-wall injections of BPC-157, yet the study lacked placebo controls, long-term follow-up, and was published in a non-indexed, alternative medicine journal

Gastrointestinal Research Applications Mucosal Protection and Healing BPC-157 research has extensively documented gastroprotective and intestinal healing effects