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Signs of the disease often include: Constitutional symptoms: fatigue, lethargy, loss of appetite, and weight loss Neurological changes: headaches, confusion, difficulty focusing, memory loss, cognitive decline, numbness, and balance issues Psychiatric effects: emotional instability, depression, personality changes, psychosis Otolaryngologic symptoms: loss or change in the sense of taste, inflammation of the tongue Cardiopulmonary indications: palpitations, difficulty breathing Gastrointestinal problems: indigestion, diarrhea, reduced appetite Patients with advanced pernicious anemia may also have noticeable physical characteristics such as pale or yellowing skin, dry skin, tender tongue, and rapid heart rate

Vitamin B12s benefits for the brain are many: It helps make myelin, speeding up nerve signals

10.1016/j.biopha.2016.10.036 196 ZhaoJ.LeiH

To store bacteriostatic water for injections simply:: Find a relatively cool location, between 60 - 80 degrees Fahrenheit