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Their efficacy in treating both AUD and metabolic disorders, including obesity and type 2 diabetes mellitus (T2DM), offers a compelling additional clinical rationale for their use [22, 23]

For instance, self-activated cascade nanozyme, f-FeNC@GOx are activated in the presence of glucose can activate highly toxic hydroxyl radicals (OH), develops ability to eradicate bacteria and promotes wound healing [176]

In addition to its antimalarial effect, cinchonine has been reported to inhibit human platelet aggregation via reducing calcium ion influx and inhibiting the protein kinase C pathway in platelets