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A 2025 study in Aging Cell confirmed these findings in both normal epithelial and fibroblast cell lines, identifying hTERT upregulation as the primary mechanism in normal cells (4)

Exosomes derived from mesenchymal stem cells reverse EMT via TGF-1/Smad pathway and promote repair of damaged endometrium

Their high specificity for target receptors or enzymes often results in fewer off-target effects and improved safety profiles

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